Dampening the fire to prevent surgery- and chemotherapy-induced metastasis

Esra Güç, Jeffrey W Pollard

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

In this issue of the JCI, Panigrahy et al. demonstrate that preoperative administration of the antiinflammatory drug ketorolac or specialized proresolving mediators (SPM) called resolvins increases disease-free survival rates and prevents metastasis after surgery and chemotherapy in mouse models of cancer. The antitumor response was partially mediated by tumor-specific T cell immunity and immunological memory.

Original languageEnglish
JournalJournal of Clinical Investigation
Publication statusPublished - 17 Jun 2019


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