Death of a trypanosome: a selfish altruism. Death of a trypanosome: a selfish altruism.

Research output: Contribution to journalLiterature reviewpeer-review

Abstract / Description of output

African trypanosomes and some related parasitic protozoa are affected by a form of programmed cell death (PCD) that shows typical hallmarks of apoptosis. Although it has been speculated that PCD has a function in life-cycle progression and the struggle for survival of these parasites, no satisfactory model has yet been proposed for the molecular mechanism(s) of PCD in protozoa, raising questions about its physiological relevance in these organisms. As we discuss here, the most important point that needs to be addressed is whether a single-celled organism can undertake a process that is considered altruistic.
Original languageEnglish
Pages (from-to)536-542
Number of pages7
JournalTrends in Parasitology
Publication statusPublished - 2006

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