Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• Protein Tyrosine Phosphatase 100%
• T Cell Receptor 5%
• CRISPR/Cas9 5%
• Genetic Manipulation 5%
• Cell Function 5%
• Transcription Factors 5%
• Monoclonal Antibody 5%
• CD8 5%
• Interleukin 2 5%
• Tumor-Associated Macrophage 5%
• NFIL3 5%

Immunology and Microbiology

• NFIL3 5%