Dendritic transmitter release: A comparison of two model systems

F. Bergquist, M. Ludwig

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Information flow through neurones was historically considered to be linear, with dendrites receiving information from incoming synaptic terminals, the soma processing the information and the axon carrying it to the terminal that synapses upon another cell or end organ. However, recent studies have shown that dendrites can release transmitters themselves, and thereby communicate with neighbouring structures, whether these are adjacent neurones or incoming synapses. Due to their anatomical features, the magnocellular vasopressin and oxytocin containing neurones of the hypothalamic supraoptic and paraventricular nuclei and the dopamine neurones of the substantia nigra have revealed important aspects of dendritic function including mechanisms of dendritic transmitter release.
Original languageEnglish
Pages (from-to)677-686
Number of pages10
JournalJournal of Neuroendocrinology
Volume20
Issue number6
DOIs
Publication statusPublished - Jun 2008

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