Depression in glioma: a primer for clinicians and researchers

Alasdair G Rooney, Paul D Brown, Jacob C Reijneveld, Robin Grant

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Depression is one of the leading causes of global disability, and a considerable hidden morbidity among patients with glioma. In this narrative review, we summarise what is currently known about depression in glioma, the main unanswered questions and the types of studies that should be prioritised in order to find out. We conclude by calling for a prospective Phase II study of antidepressants in depressed glioma patients, to test methodologies for a multicentre randomised controlled trial.

Original languageEnglish
Pages (from-to)230-5
Number of pages6
JournalJournal of Neurology, Neurosurgery & Psychiatry
Volume85
Issue number2
DOIs
Publication statusPublished - Feb 2014

Keywords

  • Antidepressive Agents
  • Clinical Trials as Topic
  • Depression
  • Glioma
  • Humans

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