Depression in glioma: a primer for clinicians and researchers

Alasdair G Rooney, Paul D Brown, Jacob C Reijneveld, Robin Grant

Research output: Contribution to journalLiterature reviewpeer-review


Depression is one of the leading causes of global disability, and a considerable hidden morbidity among patients with glioma. In this narrative review, we summarise what is currently known about depression in glioma, the main unanswered questions and the types of studies that should be prioritised in order to find out. We conclude by calling for a prospective Phase II study of antidepressants in depressed glioma patients, to test methodologies for a multicentre randomised controlled trial.

Original languageEnglish
Pages (from-to)230-5
Number of pages6
JournalJournal of Neurology, Neurosurgery & Psychiatry
Issue number2
Publication statusPublished - Feb 2014


  • Antidepressive Agents
  • Clinical Trials as Topic
  • Depression
  • Glioma
  • Humans

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