Abstract / Description of output
Developing methods to produce biomimetic lipid-based vesicles is a logical step towards understanding biomembranes and even to realize the bottom-up construction of artificial cells. In this paper, we present our developments using PDMS-based microfluidics for the production of giant unilamellar vesicles (GUVs). Not only do we have a working design that can consistently produce GUVs of specific size, but our design avoids usage of unwanted surfactants or additives such as block co-polymers, poly-vinyl alcohol, and glycerol. Overall, our work represents a major advancement for high-throughput production of lipid-based vesicles.
Original language | English |
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Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 362-363 |
Number of pages | 2 |
Volume | 1 |
ISBN (Electronic) | 9781733419000 |
ISBN (Print) | 9781713818526 |
Publication status | Published - 2019 |
Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019 |
Conference
Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
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Country/Territory | Switzerland |
City | Basel |
Period | 27/10/19 → 31/10/19 |
Keywords / Materials (for Non-textual outputs)
- Double emulsion
- Giant lipid vesicles
- High-throughput
- Surfactant-free