Detection of a novel DNA virus (TTV) in blood donors and blood products

P Simmonds, F Davidson, C Lycett, L E Prescott, D M MacDonald, J Ellender, P L Yap, C A Ludlam, G H Haydon, J Gillon, L M Jarvis

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

A newly discovered DNA virus, transfusion-transmitted virus (TTV), has been implicated as a cause of post-transfusion hepatitis. We investigated the frequency of TTV viraemia in UK blood donors, and the extent to which TTV contaminates blood products such as factor VIII and IX clotting factors. We also investigated the possible aetiological role of TTV in cryptogenic fulminant hepatic failure (FHF).
Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalThe Lancet
Volume352
Issue number9123
DOIs
Publication statusPublished - 18 Jul 1998

Keywords / Materials (for Non-textual outputs)

  • Adult
  • Aged
  • Blood Component Transfusion
  • Blood Donors
  • Child
  • DNA Viruses
  • Female
  • Great Britain
  • Hemophilia A
  • Hepatic Encephalopathy
  • Hepatitis, Viral, Human
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Viremia

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