Detection of Chlamydia trachomatis in genital swabs: comparison of commercial and in house amplification methods with culture

R M Shattock, C Patrizio, P Simmonds, S Sutherland

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

To evaluate the sensitivity of the Roche Cobas, Roche Amplicor plate kit, ligase chain reaction (LCR), and an in house polymerase chain reaction (PCR) by titration of purified elementary bodies (EB) and also to test 245 urethral and endocervical specimens for Chlamydia trachomatis by the four assays as well as conventional culture.
Original languageEnglish
Pages (from-to)289-93
Number of pages5
JournalSexually Transmitted Infections
Volume74
Issue number4
DOIs
Publication statusPublished - Aug 1998

Keywords / Materials (for Non-textual outputs)

  • Bacterial Outer Membrane Proteins
  • Chlamydia Infections
  • Chlamydia trachomatis
  • DNA, Bacterial
  • Female
  • Humans
  • Ligases
  • Male
  • Polymerase Chain Reaction
  • Sensitivity and Specificity
  • Urethral Diseases

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