Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18

EORTC Quality of Life Group; Jane M Blazeby; Elspeth Currie; Benny C Y Zee; Wei-Chu Chie; Ronnie T Poon; O James Garden

doi:10.1016/j.ejca.2004.06.033

Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18

EORTC Quality of Life Group, Jane M Blazeby, Elspeth Currie, Benny C Y Zee, Wei-Chu Chie, Ronnie T Poon, O James Garden

Research output: Contribution to journal › Article › peer-review

Abstract

Measurement of quality of life (QoL) in hepatocellular carcinoma (HCC) requires assessment of factors related to chronic liver disease, as well as issues related to the primary tumour and its treatment. This study describes the development of a questionnaire module in patients from Europe, as well as Taiwan and Hong Kong. The questionnaire was developed according to the European Organisation for Research and Treatment of Cancer (EORTC) QoL Group guidelines. Twenty nine QoL issues were identified from a literature search. Semi-structured interviews with patients (n=32) and health-care professionals (n=10) reduced the issues to 22 items forming a provisional questionnaire. This was tested in 158 patients from three countries. Descriptive statistics and clinical judgement reduced the module to 18 items conceptualised as containing six scales and two single item. This study recommends the EORTC QLQ-HCC18 to accompany the QLQ-C30 to measure QoL in clinical trials in HCC.

Original language	English
Pages (from-to)	2439-44
Number of pages	6
Journal	European journal of cancer (Oxford, England : 1990)
Volume	40
Issue number	16
DOIs	https://doi.org/10.1016/j.ejca.2004.06.033
Publication status	Published - Nov 2004

Keywords / Materials (for Non-textual outputs)

Adult
Aged
Carcinoma, Hepatocellular
Female
Humans
Liver Neoplasms
Male
Middle Aged
Quality of Life
Questionnaires

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10.1016/j.ejca.2004.06.033

Cite this

EORTC Quality of Life Group, Blazeby, J. M., Currie, E., Zee, B. C. Y., Chie, W.-C., Poon, R. T., & Garden, O. J. (2004). Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18. European journal of cancer (Oxford, England : 1990), 40(16), 2439-44. https://doi.org/10.1016/j.ejca.2004.06.033

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title = "Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18",

abstract = "Measurement of quality of life (QoL) in hepatocellular carcinoma (HCC) requires assessment of factors related to chronic liver disease, as well as issues related to the primary tumour and its treatment. This study describes the development of a questionnaire module in patients from Europe, as well as Taiwan and Hong Kong. The questionnaire was developed according to the European Organisation for Research and Treatment of Cancer (EORTC) QoL Group guidelines. Twenty nine QoL issues were identified from a literature search. Semi-structured interviews with patients (n=32) and health-care professionals (n=10) reduced the issues to 22 items forming a provisional questionnaire. This was tested in 158 patients from three countries. Descriptive statistics and clinical judgement reduced the module to 18 items conceptualised as containing six scales and two single item. This study recommends the EORTC QLQ-HCC18 to accompany the QLQ-C30 to measure QoL in clinical trials in HCC.",

keywords = "Adult, Aged, Carcinoma, Hepatocellular, Female, Humans, Liver Neoplasms, Male, Middle Aged, Quality of Life, Questionnaires",

author = "{EORTC Quality of Life Group} and Blazeby, {Jane M} and Elspeth Currie and Zee, {Benny C Y} and Wei-Chu Chie and Poon, {Ronnie T} and Garden, {O James}",

year = "2004",

month = nov,

doi = "10.1016/j.ejca.2004.06.033",

language = "English",

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EORTC Quality of Life Group, Blazeby, JM, Currie, E, Zee, BCY, Chie, W-C, Poon, RT & Garden, OJ 2004, 'Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18', European journal of cancer (Oxford, England : 1990), vol. 40, no. 16, pp. 2439-44. https://doi.org/10.1016/j.ejca.2004.06.033

Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18. / EORTC Quality of Life Group; Blazeby, Jane M; Currie, Elspeth et al.
In: European journal of cancer (Oxford, England : 1990), Vol. 40, No. 16, 11.2004, p. 2439-44.

Research output: Contribution to journal › Article › peer-review

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AU - Zee, Benny C Y

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AB - Measurement of quality of life (QoL) in hepatocellular carcinoma (HCC) requires assessment of factors related to chronic liver disease, as well as issues related to the primary tumour and its treatment. This study describes the development of a questionnaire module in patients from Europe, as well as Taiwan and Hong Kong. The questionnaire was developed according to the European Organisation for Research and Treatment of Cancer (EORTC) QoL Group guidelines. Twenty nine QoL issues were identified from a literature search. Semi-structured interviews with patients (n=32) and health-care professionals (n=10) reduced the issues to 22 items forming a provisional questionnaire. This was tested in 158 patients from three countries. Descriptive statistics and clinical judgement reduced the module to 18 items conceptualised as containing six scales and two single item. This study recommends the EORTC QLQ-HCC18 to accompany the QLQ-C30 to measure QoL in clinical trials in HCC.

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KW - Humans

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ER -

Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18

Abstract

Keywords / Materials (for Non-textual outputs)

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