Development of photostable near-infrared cyanine dyes

Animesh Samanta, Marc Vendrell, Rajkumar Das, Young-Tae Chang

Research output: Contribution to journalArticlepeer-review

Abstract

With the emerging interest in optical in vivo imaging, there is an increasing demand of photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine tricarbocyanine structure with improved photostability (CyNA) and its combinatorial derivatization to render CyNA-414 as a NIR-fluorescent dye with stronger emission intensity and higher photostability than the NIR standard IndoCyanine Green (ICG).

Original languageEnglish
Pages (from-to)7406-7408
Number of pages3
JournalChemical Communications
Volume46
Issue number39
DOIs
Publication statusPublished - 2010

Keywords

  • FLUORESCENT-PROBES
  • IN-VIVO
  • BACTERIAL-INFECTION
  • SUBSTITUENTS
  • CHROMOPHORE
  • LIGAND
  • TUMORS
  • CELLS

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