Abstract
A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported. Using an ultrasensitive and specific protein misfolding cyclic amplification-based assay for detecting variant CJD prions in cerebrospinal fluid, we discriminated this heterozygous case of variant CJD from cases of sporadic CJD.
Original language | English |
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Pages (from-to) | 1364-1366 |
Number of pages | 3 |
Journal | Emerging Infectious Diseases |
Volume | 24 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2018 |