TY - JOUR
T1 - Diagnostic potential of saccadometry in progressive supranuclear palsy
AU - Antoniades, Chrystalina A
AU - Bak, Thomas H
AU - Carpenter, R H S
AU - Hodges, John R
AU - Barker, Roger A
PY - 2007
Y1 - 2007
N2 - Progressive supranuclear palsy (PSP), an atypical parkinsonian syndrome characterized by extrapyramidal features, imbalance, supranuclear gaze paresis and dementia, can be difficult to diagnose, especially in the early stages. From the clinician's point of view, the main difficulty with this disorder is the inability to provide an accurate diagnosis, at least for the initial stages of the disease, where symptoms are often confused with other parkinsonian disorders. This inability complicates the recruitment of patients with early-stage parkinsonism to trials of disease-modifying therapy.
AB - Progressive supranuclear palsy (PSP), an atypical parkinsonian syndrome characterized by extrapyramidal features, imbalance, supranuclear gaze paresis and dementia, can be difficult to diagnose, especially in the early stages. From the clinician's point of view, the main difficulty with this disorder is the inability to provide an accurate diagnosis, at least for the initial stages of the disease, where symptoms are often confused with other parkinsonian disorders. This inability complicates the recruitment of patients with early-stage parkinsonism to trials of disease-modifying therapy.
U2 - 10.2217/17520363.1.4.487
DO - 10.2217/17520363.1.4.487
M3 - Article
C2 - 20477368
SN - 1752-0371
VL - 1
SP - 487
EP - 490
JO - Biomarkers in medicine
JF - Biomarkers in medicine
IS - 4
ER -