TY - JOUR
T1 - Differences in severe exacerbations rates and health care utilisation in COPD populationsin the UK and France
AU - Whittaker, Hannah R
AU - Van Ganse, Eric
AU - Dalon, Faustine
AU - Nolin, Maeva
AU - Marrant Micallef, Claire
AU - Pison, Christophe
AU - Ryan, Dermot
AU - Deslée, Gaetan
AU - Quint, Jennifer K
AU - Belhassen, Manon
N1 - Funding Information:
Data may be obtained from a third party and are not publicly available. Data are available on request from the Clinical Practice Research Datalink (CPRD). Their provision requires the purchase of a license and our license does not permit us to make them publicly available to all. We used data from the version collected in February 2020. To allow identical data to be obtained by others, via the purchase of a license, we will provide the code lists on request. Licenses are available from the CPRD ( http://www.cprd.com ): The Clinical Practice Research Datalink Group, The Medicines and Healthcare products Regulatory Agency, 10 South Colonnade, Canary Wharf, London E14 4PU.This research was supported by the NIHR Imperial Biomedical Research Centre (BRC) and PELyon. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. Regarding EGB data, due to NHS and SNDS rules, no data sharing is possible as access to data is restricted to habilitated and qualified researchers (MN is habilitated and qualified).
Funding Information:
HW reports grants from GSK, AZ and BI, outside the submitted work. JKQ reports grants and personal fees from British Lung Foundation, AZ, Asthma UK, BI, Bayer, GSK, MRC and Chiesi, outside the submitted work. MN, CM-M, MB and FD are employees of PELyon. EVG is the scientific advisor of PELyon. CP received support from AZ, BI, GSK, Chiesi and Novartis to attend medical meetings and fees for conferences.
Funding Information:
This research was supported by the NIHR Imperial Biomedical Research Centre (BRC) and PELyon. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. Regarding EGB data, due to NHS and SNDS rules, no data sharing is possible as access to data is restricted to habilitated and qualified researchers (MN is habilitated and qualified)
Publisher Copyright:
©
PY - 2022/8/9
Y1 - 2022/8/9
N2 - INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality in Europe; however, it is important to understand how clinical practice patterns differ between countries and how this might relate to disease outcomes, to identify ways of improving local disease management. We aimed to describe and compare the management of patients with COPD in the UK and France between 2008 and 2017.METHODS: We used data from the Clinical Practice Research Datalink GOLD and Hospital Episode Statistics in the UK and the Echantillon Généraliste des Bénéficiaire in France to identify patients with COPD each year between 2008 and 2017. We compared patient characteristics, all-cause mortality and COPD exacerbations each year between 2008 and 2017 for patients in the UK and France separately. Health care utilisation and COPD exacerbations in 2017 were compared between France and the UK using t-tests and χ
2 tests.
RESULTS: Patients with COPD were similar in gender and comorbidities in both countries. Incidence of COPD exacerbations remained stable in the UK and France between 2007 and 2017. In 2017, the proportion of all-cause and COPD-related hospitalisations was greater in the UK than in France (43.9% vs 32.8% and 8.3% vs 4.9%, respectively; p<0.001) as was the proportion of patients visiting accident and emergency (A&E) (39.8% vs 16.2%, respectively; p<0.001). In addition, the mean length of stay in hospital for COPD-related causes was shorter in the UK than in France (6.2 days (SD 8.4) vs 10.5 days (SD 9.1), respectively; p<0.001).DISCUSSION: Overall, UK patients were more likely to go to A&E, be hospitalised for COPD-related causes and stay in hospital for fewer days after being admitted for COPD-related reasons compared with patients in France, illustrating a difference in health-seeking behaviours and access to healthcare.
AB - INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality in Europe; however, it is important to understand how clinical practice patterns differ between countries and how this might relate to disease outcomes, to identify ways of improving local disease management. We aimed to describe and compare the management of patients with COPD in the UK and France between 2008 and 2017.METHODS: We used data from the Clinical Practice Research Datalink GOLD and Hospital Episode Statistics in the UK and the Echantillon Généraliste des Bénéficiaire in France to identify patients with COPD each year between 2008 and 2017. We compared patient characteristics, all-cause mortality and COPD exacerbations each year between 2008 and 2017 for patients in the UK and France separately. Health care utilisation and COPD exacerbations in 2017 were compared between France and the UK using t-tests and χ
2 tests.
RESULTS: Patients with COPD were similar in gender and comorbidities in both countries. Incidence of COPD exacerbations remained stable in the UK and France between 2007 and 2017. In 2017, the proportion of all-cause and COPD-related hospitalisations was greater in the UK than in France (43.9% vs 32.8% and 8.3% vs 4.9%, respectively; p<0.001) as was the proportion of patients visiting accident and emergency (A&E) (39.8% vs 16.2%, respectively; p<0.001). In addition, the mean length of stay in hospital for COPD-related causes was shorter in the UK than in France (6.2 days (SD 8.4) vs 10.5 days (SD 9.1), respectively; p<0.001).DISCUSSION: Overall, UK patients were more likely to go to A&E, be hospitalised for COPD-related causes and stay in hospital for fewer days after being admitted for COPD-related reasons compared with patients in France, illustrating a difference in health-seeking behaviours and access to healthcare.
KW - Disease Progression
KW - France/epidemiology
KW - Humans
KW - Patient Acceptance of Health Care
KW - Pulmonary Disease, Chronic Obstructive/epidemiology
KW - United Kingdom/epidemiology
U2 - 10.1136/bmjresp-2021-001150
DO - 10.1136/bmjresp-2021-001150
M3 - Article
C2 - 35944943
VL - 9
JO - BMJ Open Respiratory Research
JF - BMJ Open Respiratory Research
SN - 2052-4439
IS - 1
M1 - e001150
ER -