Differential Expression of Immune Defences Is Associated with Specific Host-Parasite Interactions in Insects

Carolyn Riddell, Sally Adams, Paul Schmid-Hempel, Eamonn B. Mallon

Research output: Contribution to journalArticlepeer-review

Abstract

Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broad-spectrum recognition system. An important question is whether this specificity is due to the immune response rather than some other interplay between host and parasite genotypes. By measuring the expression of putative bumblebee homologues of antimicrobial peptides in response to infection by their gut trypanosome Crithidia bombi, we demonstrate that expression differences are associated with the specific interactions.

Original languageEnglish
Article numbere7621
Pages (from-to)-
Number of pages4
JournalPLoS ONE
Volume4
Issue number10
DOIs
Publication statusPublished - 27 Oct 2009

Fingerprint

Dive into the research topics of 'Differential Expression of Immune Defences Is Associated with Specific Host-Parasite Interactions in Insects'. Together they form a unique fingerprint.

Cite this