OBJECTIVES: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging.
METHODS: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls.
RESULTS: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated.
CONCLUSIONS: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
|Number of pages||4|
|Journal||Journal of Neurology, Neurosurgery & Psychiatry|
|Publication status||Published - Dec 2003|
- Brain Edema
- Diffusion Magnetic Resonance Imaging
- Middle Aged
- Pseudotumor Cerebri