Abstract
OBJECTIVES: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging.
METHODS: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls.
RESULTS: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated.
CONCLUSIONS: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
| Original language | English |
|---|---|
| Pages (from-to) | 1693-6 |
| Number of pages | 4 |
| Journal | Journal of Neurology, Neurosurgery & Psychiatry |
| Volume | 74 |
| Issue number | 12 |
| Publication status | Published - Dec 2003 |
Keywords / Materials (for Non-textual outputs)
- Adolescent
- Adult
- Brain Edema
- Diffusion Magnetic Resonance Imaging
- Ependyma
- Female
- Humans
- Middle Aged
- Pseudotumor Cerebri