Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study

M E Bastin, S Sinha, A J Farrall, J M Wardlaw, I R Whittle

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging.

METHODS: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls.

RESULTS: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated.

CONCLUSIONS: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.

Original languageEnglish
Pages (from-to)1693-6
Number of pages4
JournalJournal of Neurology, Neurosurgery & Psychiatry
Volume74
Issue number12
Publication statusPublished - Dec 2003

Keywords / Materials (for Non-textual outputs)

  • Adolescent
  • Adult
  • Brain Edema
  • Diffusion Magnetic Resonance Imaging
  • Ependyma
  • Female
  • Humans
  • Middle Aged
  • Pseudotumor Cerebri

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