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Abstract
A novel magnetic encoding technique for performing high-throughput biological assays is presented. Electrodeposited Ni/Cu and Co/Cu multilayer pillar structures with a diameter of 15 mu m and a thickness up to 10 mu m are presented as "magnetic barcodes", where the number of unique codes possible increases exponentially with a linear increase in length. A gold cap facilitates the growth of self-assembled monolayers (SAMs), while microdrop printing allows efficient generation of large libraries of tagged probes. Coercivity-tuning techniques are used to exploit a non-proximity encoding methodology compatible with microfluidic flow. (C) 2009 Elsevier B.V. All rights reserved.
Original language | English |
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Pages (from-to) | 1662-1666 |
Number of pages | 5 |
Journal | Journal of Magnetism and Magnetic Materials |
Volume | 321 |
Issue number | 10 |
DOIs | |
Publication status | Published - May 2009 |
Keywords / Materials (for Non-textual outputs)
- Coercivity tuning
- Electrodeposition
- Nickel/copper multilayers
- Self-assembled Monolayers
- Magnetic barcodes
- NANOPARTICLES
- HYBRIDIZATION
- BIOMOLECULES
- TECHNOLOGY
- BIOSENSORS
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Dive into the research topics of 'Digital biomagnetism: Electrodeposited multilayer magnetic barcodes'. Together they form a unique fingerprint.Projects
- 1 Finished
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Basic Technology - 4 billion bases a day - practical individual genome sequencing
Bradley, M.
1/03/05 → 30/04/14
Project: Research