Digital biomagnetism: Electrodeposited multilayer magnetic barcodes

Justin J. Palfreyman, Joshaniel F. K. Cooper, Friedo van Belle, Bingyan Hong, Tom J. Hayward, Maria Lopalco, Mark Bradley, Thanos Mitrealias, J. Anthony C. Bland

Research output: Contribution to journalArticlepeer-review

Abstract

A novel magnetic encoding technique for performing high-throughput biological assays is presented. Electrodeposited Ni/Cu and Co/Cu multilayer pillar structures with a diameter of 15 mu m and a thickness up to 10 mu m are presented as "magnetic barcodes", where the number of unique codes possible increases exponentially with a linear increase in length. A gold cap facilitates the growth of self-assembled monolayers (SAMs), while microdrop printing allows efficient generation of large libraries of tagged probes. Coercivity-tuning techniques are used to exploit a non-proximity encoding methodology compatible with microfluidic flow. (C) 2009 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)1662-1666
Number of pages5
JournalJournal of Magnetism and Magnetic Materials
Volume321
Issue number10
DOIs
Publication statusPublished - May 2009

Keywords / Materials (for Non-textual outputs)

  • Coercivity tuning
  • Electrodeposition
  • Nickel/copper multilayers
  • Self-assembled Monolayers
  • Magnetic barcodes
  • NANOPARTICLES
  • HYBRIDIZATION
  • BIOMOLECULES
  • TECHNOLOGY
  • BIOSENSORS

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