Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis

J S Aguilar, D Roy, P Ghazal, E K Wagner

Research output: Contribution to journalArticlepeer-review

Abstract

Dimethyl sulfoxide (DMSO) is frequently used at a concentration of up to 95% in the formulation of antiherpetic agents because of its properties as a skin penetration enhancer. Here, we have analyzed the effect of DMSO on several parameters of Herpes Simplex Virus replication.
Original languageEnglish
Article number9
JournalBMC Infectious Diseases
Volume2
DOIs
Publication statusPublished - 2002

Keywords

  • Animals
  • Cells, Cultured
  • Cercopithecus aethiops
  • DNA Replication
  • Dimethyl Sulfoxide
  • Herpes Simplex
  • Herpesvirus 1, Human
  • Humans
  • Oligonucleotide Array Sequence Analysis
  • Rabbits
  • Vero Cells
  • Virus Replication

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