DNA sequence variation among humans and apes

Henrik Kaessmann; Ingo Ebersberger; Victor Wiebe; Rikard Erlandsson; Jim F. Wilson; Carsten Schwarz; Michaela Winkler; Svante Paeaebo

doi:10.1145/332306.332365

DNA sequence variation among humans and apes

Henrik Kaessmann^*, Ingo Ebersberger, Victor Wiebe, Rikard Erlandsson, Jim F. Wilson, Carsten Schwarz, Michaela Winkler, Svante Paeaebo

^*Corresponding author for this work

Research output: Contribution to conference › Abstract › peer-review

Abstract

Genetic sequencing was conducted to determine that DNA sequence evolution in the germ line of humans and chimpanzees. The comparison of the orthogonal sequences on the human and chimpanzee sex chromosomes show that the ZFX region display 0.8% substitutional differences between the two species, while the ZFY region display 1.5% differences. However, insertions and deletions show no difference between the two regions. Phylogenetic analyses show the sequences from the different chimpanzee subspecies to be intermixed and the distance between some chimpanzee sequences to be greater than the distance between them and the bonobo sequences.

Original language	English
Pages	175
Number of pages	1
DOIs	https://doi.org/10.1145/332306.332365
Publication status	Published - Apr 2000
Event	RECOMB 2000: 4th Annual International Conference on Computational Molecular Biology - Tokyo, Jpn Duration: 8 Apr 2000 → 11 Apr 2000

Conference

Conference	RECOMB 2000: 4th Annual International Conference on Computational Molecular Biology
City	Tokyo, Jpn
Period	8/04/00 → 11/04/00

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10.1145/332306.332365

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@conference{645436f18dcf4700831281a489516926,

title = "DNA sequence variation among humans and apes",

abstract = "Genetic sequencing was conducted to determine that DNA sequence evolution in the germ line of humans and chimpanzees. The comparison of the orthogonal sequences on the human and chimpanzee sex chromosomes show that the ZFX region display 0.8\% substitutional differences between the two species, while the ZFY region display 1.5\% differences. However, insertions and deletions show no difference between the two regions. Phylogenetic analyses show the sequences from the different chimpanzee subspecies to be intermixed and the distance between some chimpanzee sequences to be greater than the distance between them and the bonobo sequences.",

author = "Henrik Kaessmann and Ingo Ebersberger and Victor Wiebe and Rikard Erlandsson and Wilson, \{Jim F.\} and Carsten Schwarz and Michaela Winkler and Svante Paeaebo",

year = "2000",

month = apr,

doi = "10.1145/332306.332365",

language = "English",

pages = "175",

note = "RECOMB 2000: 4th Annual International Conference on Computational Molecular Biology ; Conference date: 08-04-2000 Through 11-04-2000",

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T1 - DNA sequence variation among humans and apes

AU - Kaessmann, Henrik

AU - Ebersberger, Ingo

AU - Wiebe, Victor

AU - Erlandsson, Rikard

AU - Wilson, Jim F.

AU - Schwarz, Carsten

AU - Winkler, Michaela

AU - Paeaebo, Svante

PY - 2000/4

Y1 - 2000/4

N2 - Genetic sequencing was conducted to determine that DNA sequence evolution in the germ line of humans and chimpanzees. The comparison of the orthogonal sequences on the human and chimpanzee sex chromosomes show that the ZFX region display 0.8% substitutional differences between the two species, while the ZFY region display 1.5% differences. However, insertions and deletions show no difference between the two regions. Phylogenetic analyses show the sequences from the different chimpanzee subspecies to be intermixed and the distance between some chimpanzee sequences to be greater than the distance between them and the bonobo sequences.

AB - Genetic sequencing was conducted to determine that DNA sequence evolution in the germ line of humans and chimpanzees. The comparison of the orthogonal sequences on the human and chimpanzee sex chromosomes show that the ZFX region display 0.8% substitutional differences between the two species, while the ZFY region display 1.5% differences. However, insertions and deletions show no difference between the two regions. Phylogenetic analyses show the sequences from the different chimpanzee subspecies to be intermixed and the distance between some chimpanzee sequences to be greater than the distance between them and the bonobo sequences.

UR - https://www.scopus.com/pages/publications/0033707328

U2 - 10.1145/332306.332365

DO - 10.1145/332306.332365

M3 - Abstract

AN - SCOPUS:0033707328

SP - 175

T2 - RECOMB 2000: 4th Annual International Conference on Computational Molecular Biology

Y2 - 8 April 2000 through 11 April 2000

ER -

DNA sequence variation among humans and apes

Abstract

Conference

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