Do HPV-negative cervical carcinomas exist?

Research output: Contribution to journalEditorialpeer-review

Abstract

There has been considerable debate regarding the existence of HPV-negative cervical carcinoma. In this issue of the journal, using well-controlled methodology, Walboomers et al. demonstrate that HPV DNA is present in almost all invasive carcinomas in a large multinational study. This indicates that HPV-negative carcinoma is extremely uncommon, if it exists at all. It also implies that HPV testing, if optimally applied, is capable of a sensitivity approaching 100 per cent. This has significant implications for cervical screening
Original languageEnglish
Pages (from-to)1
JournalThe Journal of Pathology
Volume198
Issue number1
DOIs
Publication statusPublished - 1999

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