Does arousal frequency predict daytime function?

R N Kingshott, H M Engleman, I J Deary, N J Douglas

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Patients with the sleep apnoea/hypopnoea syndrome (SANS) have impaired daytime function with demonstrable sleepiness and impaired cognition, The hypothesis that brief arousals From sleep cause these daytime impairments was tested.

One hundred and fifty patients with sleep disordered breathing were studied prospectively, comparing overnight polysomnography with daytime measures of objective sleepiness, psychological well-being and cognitive performance.

Significant, but weak (r(2)<0.1), relatonships were seen between several nocturnal measures (apnoea/hypopnoea index, arousals and desaturation variables) and daytime measures of quality of life, well-being, subjective sleepiness, symptoms and cognitive performance,The only significant relationship between nocturnal variables and objective sleepiness was a very weak correlation (r(2)<0.05) between the lowest oxygen saturation and mean maintenance of wakefulness test (MWT) result, The MWT was better correlated with daytime function than the multiple sleep latency test. This study shows a lack of strong relationships between conventional nocturnalvariables and objective sleepiness was a very weak correlation (r(2)<0.05) between the lowest oxygen saturation and mean maintenance of wakefulness test (MWT) result, The MWT was better correlated with daytime function than the multiple sleep latency test.

This study shows a lack of strong relationships between conventional nocturnal measures and daytime function in patients with sleep disordered breathing.

Original languageEnglish
Pages (from-to)1264-1270
Number of pages7
JournalEuropean Respiratory Journal
Volume12
Issue number6
Publication statusPublished - Dec 1998

Keywords / Materials (for Non-textual outputs)

  • cognitive function
  • sleep apnoea/hypopnoea syndrome
  • sleepiness
  • OBSTRUCTIVE SLEEP-APNEA
  • LATENCY TEST
  • APNOEA/HYPOPNOEA SYNDROME
  • HYPOPNEA SYNDROME
  • WAKEFULNESS TEST
  • FRAGMENTATION
  • DISORDERS
  • MAINTENANCE
  • SCALE

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