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Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker? Migration and survival of the fittest in the modern age of lifestyle-induced circadian desynchrony

Cathy A Wyse*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The variable photoperiods of Northern latitudes challenge the entrainment capacity of the circadian pacemaker, which evolved under constant photoperiods in Equatorial regions. Entrainment to the erratic photoperiods facilitated by artificial light presents an additional challenge. Metabolic dysfunction and obesity are potential consequences of such desynchronization of circadian and environmental rhythms.

Original languageEnglish
Pages (from-to)921-924
Number of pages4
JournalBioEssays
Volume34
Issue number11
Early online date30 Aug 2012
DOIs
Publication statusPublished - 1 Nov 2012

Keywords / Materials (for Non-textual outputs)

  • Biological Clocks/physiology
  • Biological Evolution
  • Circadian Rhythm/physiology
  • Disease Susceptibility/pathology
  • Geography
  • Homeostasis
  • Human Migration
  • Humans
  • Life Style
  • Obesity/physiopathology
  • Survival

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