Does right ventricular function predict survival in patients with chronic obstructive lung disease?

A J France, Robin J Prescott, W Biernacki, A L Muir, William Macnee

Research output: Contribution to journalArticlepeer-review

Abstract

Non-invasive measurements of the right ventricular ejection fraction by radionuclide ventriculography were made in 115 patients with chronic obstructive lung disease. Survival was assessed over a mean period of 918 days. The right ventricular ejection fraction was reasonably normal in most patients (mean 0.42, range 0.10-0.66) but was lower in those with peripheral oedema, indicating cor pulmonale (mean 0.31 (SD 0.07); p less than 0.0001). Right ventricular ejection fraction was related to survival, but the relationship was weak (p = 0.03) by comparison with the association between the arterial oxygen and carbon dioxide tensions and survival (both p less than 0.0001). It is concluded that, although right ventricular function is predictive of survival in patients with chronic obstructive lung disease, it is probably a reflection of severity of disease and does not directly affect the prognosis.
Original languageEnglish
Pages (from-to)621-6
Number of pages6
JournalThorax
Volume43
Issue number8
Publication statusPublished - Aug 1988

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