Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development

N D Hastie

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)293-5
Number of pages3
JournalHuman Molecular Genetics
Issue number5
Publication statusPublished - Aug 1992


  • Base Sequence
  • Child
  • DNA Mutational Analysis
  • DNA, Neoplasm
  • DNA-Binding Proteins
  • Genes, Dominant
  • Genes, Wilms Tumor
  • Humans
  • Kidney Neoplasms
  • Molecular Sequence Data
  • Syndrome
  • Urogenital Abnormalities
  • Urogenital System
  • WT1 Proteins
  • Wilms Tumor

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