Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation

Yeshi Yin; T Ryan Withers; John R W Govan; Shannon L Johnson; Hongwei D Yu

doi:10.1128/genomeA.00834-13

Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation

Yeshi Yin, T Ryan Withers, John R W Govan, Shannon L Johnson, Hongwei D Yu

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.

Original language	English
Journal	Genome announcements
Volume	1
Issue number	5
DOIs	https://doi.org/10.1128/genomeA.00834-13
Publication status	Published - 2013

Access to Document

10.1128/genomeA.00834-13

Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation.
Copyright © 2013 Yin et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.
Final published version, 123 KBLicence: Creative Commons: Attribution (CC-BY)

http://genomea.asm.org/content/1/5/e00834-13

Cite this

@article{a10eb737b19b4e1fa93a80b4becafb87,

title = "Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation",

abstract = "A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.",

author = "Yeshi Yin and Withers, {T Ryan} and Govan, {John R W} and Johnson, {Shannon L} and Yu, {Hongwei D}",

year = "2013",

doi = "10.1128/genomeA.00834-13",

language = "English",

volume = "1",

journal = "Genome announcements",

issn = "2169-8287",

publisher = "American Society for Microbiology",

number = "5",

}

TY - JOUR

T1 - Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation

AU - Yin, Yeshi

AU - Withers, T Ryan

AU - Govan, John R W

AU - Johnson, Shannon L

AU - Yu, Hongwei D

PY - 2013

Y1 - 2013

N2 - A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.

AB - A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.

U2 - 10.1128/genomeA.00834-13

DO - 10.1128/genomeA.00834-13

M3 - Article

C2 - 24115549

SN - 2169-8287

VL - 1

JO - Genome announcements

JF - Genome announcements

IS - 5

ER -

Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation

Abstract

Access to Document

Fingerprint

Cite this