An isolation technique, which does not require conventional circulators, is proposed for the realization of a simple and low-cost aperture-coupled circularly polarized antenna for application to full-duplex devices. The approach is based on the use of slotlines loops to provide surface current cancellation in specific regions of the antenna structure, leading to improved axial ratio and isolation between the ports in excess of 50 dB. Circular polarization is achieved by introducing a double-box hybrid coupler, which is optimized to obtain good matching and isolation of the quadrature signals. On this basis, both right-and left-hand circularly polarized beams are achieved by interchanging the transmitting and receiving antenna ports, enabling full-duplex operation and reconfigurability. While the antenna structure is designed for 2.45 GHz operation, one can take advantage of the proposed approach to tune the frequency of maximum isolation. Both single-element prototypes as well as a 2x2 array are fabricated and measured, showing good agreement with the simulations and validating the proposed isolation approach. The beam steering capabilities as well as the application to a Van Atta retrodirective antenna array and the possibilities of achieving delta and sum patterns for monopulse operation are also reported. The proposed full-duplex antenna can also represent an excellent solution for narrowband wireless power transmission systems.