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Abstract
The exploitation of fibre based Raman probes has been challenged by often complicated fabrication procedures and difficulties in reproducibility. Here, we have demonstrated a simple and cost-effective approach for sensing pH through an optical fibre, by employing a wax patterned filter paper-based substrate for surface enhanced Raman spectroscopy (SERS). Through this method, high reproducibilty between fibres was achieved. In addition to sensing pH, it was possible to extract fluid samples containing P.aeruginosa for further analysis. This dual purpose fibre is bronchoscope deployable, and is able to gather information about both the host and pathogen, which may lead to an improved treatment plan in future in vivo applications.
Original language | English |
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Journal | Analyst |
Early online date | 5 Oct 2018 |
DOIs | |
Publication status | E-pub ahead of print - 5 Oct 2018 |
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Dive into the research topics of 'Dual purpose fibre – SERS pH sensing and bacterial analysis'. Together they form a unique fingerprint.Projects
- 1 Finished
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Multiplexed 'Touch and Tell' Optical Molecular Sensing and Imaging
1/10/13 → 31/03/19
Project: Research