Dual purpose fibre – SERS pH sensing and bacterial analysis

Holly Fleming, Sarah Mcaughtrie, Bethany Mills, Michael G. Tanner, Angus Marks, Colin J. Campbell

Research output: Contribution to journalArticlepeer-review

Abstract

The exploitation of fibre based Raman probes has been challenged by often complicated fabrication procedures and difficulties in reproducibility. Here, we have demonstrated a simple and cost-effective approach for sensing pH through an optical fibre, by employing a wax patterned filter paper-based substrate for surface enhanced Raman spectroscopy (SERS). Through this method, high reproducibilty between fibres was achieved. In addition to sensing pH, it was possible to extract fluid samples containing P.aeruginosa for further analysis. This dual purpose fibre is bronchoscope deployable, and is able to gather information about both the host and pathogen, which may lead to an improved treatment plan in future in vivo applications.
Original languageEnglish
JournalAnalyst
Early online date5 Oct 2018
DOIs
Publication statusE-pub ahead of print - 5 Oct 2018

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