E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

Hao Huang, Derek F. Ceccarelli, Stephen Orlicky, Daniel J. St-Cyr, Amy Ziemba, Pankaj Garg, Serge Plamondon, Manfred Auer, Sachdev Sidhu, Anne Marinier, Gary Kleiger, Mike Tyers*, Frank Sicheri

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology