East Coast fever, a neglected tropical disease with an outdated vaccine approach?

Jeannine Kolakowski, Tim Connelley, Petra Lukacik, Mark Pfuhl, Dirk Werling

Research output: Contribution to journalArticlepeer-review

Abstract

Since its discovery, bovine theileriosis has caused major socioeconomic losses in sub-Saharan Africa. Acaricide resistance of the intermediate host, paucity of therapeutics, and lack of sufficiently cross-protective vaccines increase the risk of parasite spread due to global warming. Here, we highlight three important areas that require investigation to develop next-generation vaccines.

Original languageEnglish
Pages (from-to)930-932
JournalTrends in Parasitology
Volume38
Issue number11
Early online date27 Aug 2022
DOIs
Publication statusPublished - Nov 2022

Keywords

  • Theileria parva
  • cellular immunity
  • drug resistance
  • glycobiology
  • infection and treatment method (ITM)
  • protein modelling

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