EchoBASE: an integrated post-genomic database for Escherichia coli

Raju V Misra, Richard SP Horler, Wolfgang Reindl, Igor I Goryanin, Gavin H Thomas

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is to collate information from a wide range of sources to provide clues to the functions of the approximately 1500 gene products that have no confirmed cellular function. The database is built on an enhanced annotation of the updated genome sequence of strain MG1655 and the association of experimental data with the E.coli genes and their products. Experiments that can be held within EchoBASE include proteomics studies, microarray data, protein–protein interaction data, structural data and bioinformatics studies. EchoBASE also contains annotated information on ‘orphan’ enzyme activities from this microbe to aid characterization of the proteins that catalyse these elusive biochemical reactions.
Original languageEnglish
Pages (from-to)D329-D333
JournalNucleic Acids Research
Volume33
Issue numbersuppl 1
DOIs
Publication statusPublished - Jan 2005

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