TY - JOUR
T1 - Editorial: The Immunomodulatory Properties of Extracellular Vesicles From Pathogens, Immune Cells, and Non-immune Cells
AU - Poon, Ivan K. H.
AU - Gregory, Christopher D.
AU - Kaparakis-liaskos, Maria
PY - 2018/12/19
Y1 - 2018/12/19
N2 - Intercellular communication is key for immune regulation and extracellular vesicles (EVs) are emerging as important mediators of this process. EVs like exosomes, microvesicles, and apoptotic bodies are membrane-bound vesicles that can be released by both immune and non-immune cells. Although different types of EVs vary greatly in their size (~30 nm to 5μm in diameter) and mechanism of formation, it is now well-established that the cellular constituents in/on EVs (e.g., antigens, cytokines, membrane proteins, and microRNAs) can regulate a variety of immune responses. Besides mammalian cells, bacteria, fungi, and parasites can also release membrane vesicles tomodulate host immune responses. In this research topic, a collection of primary research and review papers explored the immunoregulatory properties of EVs released from immune cells, tumor cells, apoptotic cells as well as pathogens.
AB - Intercellular communication is key for immune regulation and extracellular vesicles (EVs) are emerging as important mediators of this process. EVs like exosomes, microvesicles, and apoptotic bodies are membrane-bound vesicles that can be released by both immune and non-immune cells. Although different types of EVs vary greatly in their size (~30 nm to 5μm in diameter) and mechanism of formation, it is now well-established that the cellular constituents in/on EVs (e.g., antigens, cytokines, membrane proteins, and microRNAs) can regulate a variety of immune responses. Besides mammalian cells, bacteria, fungi, and parasites can also release membrane vesicles tomodulate host immune responses. In this research topic, a collection of primary research and review papers explored the immunoregulatory properties of EVs released from immune cells, tumor cells, apoptotic cells as well as pathogens.
U2 - 10.3389/fimmu.2018.03024
DO - 10.3389/fimmu.2018.03024
M3 - Article
SN - 1664-3224
VL - 9
JO - Frontiers in Immunology
JF - Frontiers in Immunology
ER -