Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial

K C H Fearon; M F Von Meyenfeldt; A G W Moses; R Van Geenen; A Roy; D J Gouma; A Giacosa; A Van Gossum; J Bauer; M D Barber; N K Aaronson; A C Voss; M J Tisdale

doi:10.1136/gut.52.10.1479

Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial

K C H Fearon, M F Von Meyenfeldt, A G W Moses, R Van Geenen, A Roy, D J Gouma, A Giacosa, A Van Gossum, J Bauer, M D Barber, N K Aaronson, A C Voss, M J Tisdale

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

N-3 fatty acids, especially eicosapentaenoic acid (EPA), may possess anticachectic properties. This trial compared a protein and energy dense supplement enriched with n-3 fatty acids and antioxidants (experimental: E) with an isocaloric isonitrogenous control supplement (C) for their effects on weight, lean body mass (LBM), dietary intake, and quality of life in cachectic patients with advanced pancreatic cancer.

Original language	English
Pages (from-to)	1479-86
Number of pages	8
Journal	Gut
Volume	52
Issue number	10
DOIs	https://doi.org/10.1136/gut.52.10.1479
Publication status	Published - 2003

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10.1136/gut.52.10.1479

Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia
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Fearon, K. C. H., Von Meyenfeldt, M. F., Moses, A. G. W., Van Geenen, R., Roy, A., Gouma, D. J., Giacosa, A., Van Gossum, A., Bauer, J., Barber, M. D., Aaronson, N. K., Voss, A. C., & Tisdale, M. J. (2003). Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut, 52(10), 1479-86. https://doi.org/10.1136/gut.52.10.1479

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title = "Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial",

abstract = "N-3 fatty acids, especially eicosapentaenoic acid (EPA), may possess anticachectic properties. This trial compared a protein and energy dense supplement enriched with n-3 fatty acids and antioxidants (experimental: E) with an isocaloric isonitrogenous control supplement (C) for their effects on weight, lean body mass (LBM), dietary intake, and quality of life in cachectic patients with advanced pancreatic cancer.",

author = "Fearon, {K C H} and {Von Meyenfeldt}, {M F} and Moses, {A G W} and {Van Geenen}, R and A Roy and Gouma, {D J} and A Giacosa and {Van Gossum}, A and J Bauer and Barber, {M D} and Aaronson, {N K} and Voss, {A C} and Tisdale, {M J}",

year = "2003",

doi = "10.1136/gut.52.10.1479",

language = "English",

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pages = "1479--86",

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Fearon, KCH, Von Meyenfeldt, MF, Moses, AGW, Van Geenen, R, Roy, A, Gouma, DJ, Giacosa, A, Van Gossum, A, Bauer, J, Barber, MD, Aaronson, NK, Voss, AC & Tisdale, MJ 2003, 'Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial', Gut, vol. 52, no. 10, pp. 1479-86. https://doi.org/10.1136/gut.52.10.1479

TY - JOUR

T1 - Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia

T2 - a randomised double blind trial

AU - Fearon, K C H

AU - Von Meyenfeldt, M F

AU - Moses, A G W

AU - Van Geenen, R

AU - Roy, A

AU - Gouma, D J

AU - Giacosa, A

AU - Van Gossum, A

AU - Bauer, J

AU - Barber, M D

AU - Aaronson, N K

AU - Voss, A C

AU - Tisdale, M J

PY - 2003

Y1 - 2003

N2 - N-3 fatty acids, especially eicosapentaenoic acid (EPA), may possess anticachectic properties. This trial compared a protein and energy dense supplement enriched with n-3 fatty acids and antioxidants (experimental: E) with an isocaloric isonitrogenous control supplement (C) for their effects on weight, lean body mass (LBM), dietary intake, and quality of life in cachectic patients with advanced pancreatic cancer.

AB - N-3 fatty acids, especially eicosapentaenoic acid (EPA), may possess anticachectic properties. This trial compared a protein and energy dense supplement enriched with n-3 fatty acids and antioxidants (experimental: E) with an isocaloric isonitrogenous control supplement (C) for their effects on weight, lean body mass (LBM), dietary intake, and quality of life in cachectic patients with advanced pancreatic cancer.

U2 - 10.1136/gut.52.10.1479

DO - 10.1136/gut.52.10.1479

M3 - Article

C2 - 12970142

SN - 0017-5749

VL - 52

SP - 1479

EP - 1486

JO - Gut

JF - Gut

IS - 10

ER -

Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial

Abstract / Description of output

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