Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, María Soler Artigas, Louise V Wain, Emmanouela Repapi, Ma'en Obeidat, Ian Sayers, Paul R Burton, Toby Johnson, Jing Hua Zhao, Eva Albrecht, Anna F Dominiczak, Shona M Kerr, Blair H Smith, Gemma Cadby, Jennie Hui, Lyle J Palmer, Aroon D Hingorani, S Goya Wannamethee, Peter H Whincup, Shah EbrahimGeorge Davey Smith, Inês Barroso, Ruth J F Loos, Nicholas J Wareham, Cyrus Cooper, Elaine Dennison, Seif O Shaheen, Jason Z Liu, Jonathan Marchini, Santosh Dahgam, Asa Torinsson Naluai, Anna-Carin Olin, Stefan Karrasch, Joachim Heinrich, Holger Schulz, Tricia M McKeever, Ian D Pavord, Markku Heliövaara, Samuli Ripatti, Ida Surakka, John D Blakey, Mika Kähönen, John R Britton, Fredrik Nyberg, John W Holloway, Debbie A Lawlor, Richard W Morris, Alan L James, Cathy M Jackson, Ian P Hall, Martin D Tobin

Research output: Contribution to journalArticlepeer-review

Abstract

Genomic loci are associated with FEV1 or the ratio of FEV1 to FVC in population samples, but their association with chronic obstructive pulmonary disease (COPD) has not yet been proven, nor have their combined effects on lung function and COPD been studied.
Original languageEnglish
Pages (from-to)786-95
Number of pages10
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume184
Issue number7
DOIs
Publication statusPublished - 2011

Fingerprint

Dive into the research topics of 'Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function'. Together they form a unique fingerprint.

Cite this