Effect of glacial acetic acid pre-treatment of cervical liquid-based cytology specimens on the molecular detection of human papillomavirus

C Moore, Kate Cuschieri, F McQueen, E Duvall, C Graham, H A Cubie

Research output: Contribution to journalArticlepeer-review

Abstract

Cytology laboratories routinely treat cervical liquid-based cytology (LBC) specimens that are heavily contaminated with blood with glacial acetic acid (GAA) in order to lyse red blood cells and facilitate assessment. However, the impact on downstream human papillomavirus (HPV) detection is not well understood. This study examines the effect of GAA pre-treatment of ThinPrep(®) Preservcyt(®) specimens on the molecular detection of HPV.
Original languageEnglish
Pages (from-to)314-20
Number of pages7
JournalCytopathology
Volume24
Issue number5
DOIs
Publication statusPublished - Oct 2013

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