Effect of network structure on the bubble dislodgment and pressure distribution in microfluidic networks with multiple bifurcations

Cong Chao, Xiaoqiang Jin, Xianfeng Fan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Bubble lodgment in a network with multiple bifurcations, such as blood vessels and microfluidic networks, is a crucial issue in many biological and chemical processes. However, it has not been quantitatively investigated, particularly the impact of the network structure on the bubble dislodgment, and the distribution of the applied overall pressure in each channel. In this study, ‘point-volume-point’ networks with multiple bifurcations are designed with smoothly-changed flowpath. Over 500 experiments were conducted to characterize the effect of network structure on the bubble dislodgment. The distribution of the overall pressure in an individual channel j is characterized through a parameter cj where a bubble is lodged in microchannel j. The results indicate that the cj value is smaller for the channel with complicated surrounding networks. A higher bifurcating angle of microchannel j results in a larger cj value of the microchannel j and a lower cj value of the proximal microchannel.

Original languageEnglish
Article number115176
JournalChemical Engineering Science
Volume209
Early online date24 Aug 2019
DOIs
Publication statusPublished - 14 Dec 2019

Keywords

  • Bifurcating angle
  • Bubble motion
  • Dislodging pressure
  • Microfluidic devices
  • Multiple bifurcations
  • Network structure

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