Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus

T. Opriessnig, R.B. Evans, D. Cavanaugh, F.J. Pallares, P.G. Halbur, M. Fenaux, X.J. Meng, S. Yu, E.L. Thacker, J.M. Gallup, K.M. Lager

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The objectives of this study were to determine if coinfection of segregated early weaned (SEW) pigs with porcine circovirus type 2 (PCV2) and porcine parvovirus (PPV) induces an increase in the incidence of post-weaning multisystemic wasting syndrome (PMWS) compared to singular PCV2 infection, and to determine if vaccination against PPV protects pigs against PMWS associated with PCV2/PPV coinfection in SEW pigs. Seventy, 3-week-old, SEW pigs were randomly assigned to one of the five groups. Pigs in group 1 (n=14) served as the negative controls, group 2 pigs (n=14) were inoculated with PCV2, group 3 pigs (n=12) were inoculated with PPV, groups 4 (n=16) and 5 (n=14) pigs were inoculated with both PCV2 and PPV. Pigs in groups 1-3 and 5 were vaccinated with two doses of a killed parvovirus-leptospira-erysipelothrix (PLE) vaccine prior to inoculation. The PCV2/PPV-coinfected pigs (groups 4 and 5) had significantly (P
Original languageEnglish
Pages (from-to)209-220
Number of pages12
JournalVeterinary Microbiology
Volume98
Issue number3-4
DOIs
Publication statusPublished - 5 Mar 2004

Fingerprint

Dive into the research topics of 'Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus'. Together they form a unique fingerprint.

Cite this