TY - JOUR
T1 - Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus
AU - Opriessnig, T.
AU - Evans, R.B.
AU - Cavanaugh, D.
AU - Pallares, F.J.
AU - Halbur, P.G.
AU - Fenaux, M.
AU - Meng, X.J.
AU - Yu, S.
AU - Thacker, E.L.
AU - Gallup, J.M.
AU - Lager, K.M.
PY - 2004/3/5
Y1 - 2004/3/5
N2 - The objectives of this study were to determine if coinfection of segregated early weaned (SEW) pigs with porcine circovirus type 2 (PCV2) and porcine parvovirus (PPV) induces an increase in the incidence of post-weaning multisystemic wasting syndrome (PMWS) compared to singular PCV2 infection, and to determine if vaccination against PPV protects pigs against PMWS associated with PCV2/PPV coinfection in SEW pigs. Seventy, 3-week-old, SEW pigs were randomly assigned to one of the five groups. Pigs in group 1 (n=14) served as the negative controls, group 2 pigs (n=14) were inoculated with PCV2, group 3 pigs (n=12) were inoculated with PPV, groups 4 (n=16) and 5 (n=14) pigs were inoculated with both PCV2 and PPV. Pigs in groups 1-3 and 5 were vaccinated with two doses of a killed parvovirus-leptospira-erysipelothrix (PLE) vaccine prior to inoculation. The PCV2/PPV-coinfected pigs (groups 4 and 5) had significantly (P
AB - The objectives of this study were to determine if coinfection of segregated early weaned (SEW) pigs with porcine circovirus type 2 (PCV2) and porcine parvovirus (PPV) induces an increase in the incidence of post-weaning multisystemic wasting syndrome (PMWS) compared to singular PCV2 infection, and to determine if vaccination against PPV protects pigs against PMWS associated with PCV2/PPV coinfection in SEW pigs. Seventy, 3-week-old, SEW pigs were randomly assigned to one of the five groups. Pigs in group 1 (n=14) served as the negative controls, group 2 pigs (n=14) were inoculated with PCV2, group 3 pigs (n=12) were inoculated with PPV, groups 4 (n=16) and 5 (n=14) pigs were inoculated with both PCV2 and PPV. Pigs in groups 1-3 and 5 were vaccinated with two doses of a killed parvovirus-leptospira-erysipelothrix (PLE) vaccine prior to inoculation. The PCV2/PPV-coinfected pigs (groups 4 and 5) had significantly (P
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-10744232088&partnerID=8YFLogxK
U2 - 10.1016/j.vetmic.2003.11.006
DO - 10.1016/j.vetmic.2003.11.006
M3 - Article
AN - SCOPUS:10744232088
VL - 98
SP - 209
EP - 220
JO - Veterinary Microbiology
JF - Veterinary Microbiology
SN - 0378-1135
IS - 3-4
ER -