Effects of age on antiretroviral plasma drug concentration in HIV-infected subjects undergoing routine therapeutic drug monitoring

UK Collaborative HIV Cohort Study, Alan Winston, Sophie Jose, Sara Gibbons, David Back, Wolfgang Stohr, Frank Post, Martin Fisher, Brian Gazzard, Mark Nelson, Richard Gilson, Chloe Orkin, Margaret Johnson, Adrian Palfreeman, David Chadwick, Clifford Leen, Achim Schwenk, Jane Anderson, Mark Gompels, David DunnSaye Khoo, Caroline Sabin

Research output: Contribution to journalArticlepeer-review

Abstract

The pharmacokinetic and pharmacodynamic effects of antiretroviral therapy may differ in older compared with younger subjects with HIV infection. We aimed to assess factors associated with plasma antiretroviral drug exposure, including age, within a large HIV-infected cohort undergoing therapeutic drug monitoring (TDM).
Original languageEnglish
Pages (from-to)1354-9
Number of pages6
JournalJournal of Antimicrobial Chemotherapy
Volume68
Issue number6
DOIs
Publication statusPublished - Jun 2013

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