Abstract / Description of output
In animals, peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma agonists down-regulate 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) mRNA and activity in liver and adipose tissue, respectively, and PPARgamma agonists reduce ACTH secretion from corticotrope cells.
Original language | English |
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Pages (from-to) | 1848-56 |
Number of pages | 9 |
Journal | The Journal of Clinical Endocrinology & Metabolism (JCEM) |
Volume | 92 |
Issue number | 5 |
DOIs | |
Publication status | Published - Feb 2007 |