Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation

Luveris Pretreatment Group, Cedrin I Durnerin, K Erb, R Fleming, H Hillier, S G Hillier, C M Howles, J-N Hugues, A Lass, H Lyall, P Rasmussen, J Thong, I Traynor, L Westergaard, R Yates

Research output: Contribution to journalArticlepeer-review

Abstract

The role of LH in sensitizing antral follicles to FSH is unclear. LH is required for normal hormone production and normal oocyte and embryo development, but follicular responses to LH may depend upon the stage of development. Potential roles at the early follicular phase were explored in a clinical setting by employing a sequential approach to stimulation by recombinant human (r-h) LH followed by r-hFSH in women who were profoundly down-regulated by depo GnRH agonist.
Original languageEnglish
Pages (from-to)421-6
Number of pages6
JournalHuman Reproduction
Volume23
Issue number2
DOIs
Publication statusPublished - Feb 2008

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