Abstract / Description of output
Organocatalytic α-sulfenylation of substituted piperazine-2,5-diones is reported through the use of cinchona alkaloids as Lewis bases and electrophilic sulfur transfer reagents. 1-Phenylsulfanyl[1,2,4]triazole, a novel sulfur transfer reagent, gave excellent product yields with a number of substituted piperazine-2,5-diones under mild conditions. Catalyst loading, stoichiometry of sulfur electrophile, temperature, and solvent were optimized to achieve high product yields.
Original language | English |
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Pages (from-to) | 4310-4313 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue number | 30 |
DOIs | |
Publication status | Published - 29 Jul 2009 |