Electrolyte-Gated FET-based Sensing of Immobilized Amphoteric Molecules Including the Variability in Affinity of the Reactive Sites

Naveen Kumar*, Cesar Pascual Garcia, Ali Rezaei, Ankit Dixit, Asen Asenov, Vihar Georgiev

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract / Description of output

In this work, we developed a unique computational approach that allowed us to detect immobilized amphoteric molecules on the surface of an electrolyte-gated FET-based sensor. Our simulation methodology is based on a combination of the Site-Binding and Gouy-Chapman-Stern models which are solved self-consistently. Our analytical model allows us to describe the surface charge density due to the protonation and deprotonation of the reactive sites of amphoteric molecules. Moreover, we have analyzed the effect of variability in the affinity constant of reactive sites. We also studied the effect of random dopant fluctuations in nanowire FET using in-house simulator NESS to account for the reliability issues in FET-based sensor technology.

Original languageEnglish
Title of host publication2023 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2023
PublisherInstitute of Electrical and Electronics Engineers
Pages377-380
Number of pages4
ISBN (Electronic)9784863488038
DOIs
Publication statusPublished - 20 Nov 2023
Event2023 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2023 - Kobe, Japan
Duration: 27 Sept 202329 Sept 2023

Publication series

NameInternational Conference on Simulation of Semiconductor Processes and Devices, SISPAD

Conference

Conference2023 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2023
Country/TerritoryJapan
CityKobe
Period27/09/2329/09/23

Keywords / Materials (for Non-textual outputs)

  • Amphoteric Molecules
  • Dissociation Constant Variation
  • Fingerprints
  • Gouy-Chapman-Stern Model
  • Nanowire FET
  • Random-Dopant Fluctuations
  • Scattering
  • Site-Binding Model

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