Elevated cerebrospinal fluid vasopressin in motor neuron disease

J R Seckl; S L Lightman; R J Guiloff

doi:10.1136/jnnp.50.6.795

Elevated cerebrospinal fluid vasopressin in motor neuron disease

J R Seckl, S L Lightman, R J Guiloff

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

CSF vasopressin levels were significantly elevated in eight patients with motor neuron disease (2.5 +/- 0.4 pmol/l) compared with controls (0.7 +/- 0.1 pmol/l). CSF oxytocin and plasma vasopressin concentrations were similar in the two groups. This finding may be a primary part of the disease process or an epiphenomenon related to increased autonomic and descending pathway activity secondary to abnormal function and/or loss of anterior horn cells.

Original language	English
Pages (from-to)	795-7
Number of pages	3
Journal	Journal of Neurology, Neurosurgery & Psychiatry
Volume	50
Issue number	6
DOIs	https://doi.org/10.1136/jnnp.50.6.795
Publication status	Published - 1987

Access to Document

10.1136/jnnp.50.6.795

http://jnnp.bmj.com/content/50/6/795.

Cite this

@article{dd11360ae0b349bdaafbf2962e7d129e,

title = "Elevated cerebrospinal fluid vasopressin in motor neuron disease",

abstract = "CSF vasopressin levels were significantly elevated in eight patients with motor neuron disease (2.5 +/- 0.4 pmol/l) compared with controls (0.7 +/- 0.1 pmol/l). CSF oxytocin and plasma vasopressin concentrations were similar in the two groups. This finding may be a primary part of the disease process or an epiphenomenon related to increased autonomic and descending pathway activity secondary to abnormal function and/or loss of anterior horn cells.",

author = "Seckl, {J R} and Lightman, {S L} and Guiloff, {R J}",

year = "1987",

doi = "10.1136/jnnp.50.6.795",

language = "English",

volume = "50",

pages = "795--7",

journal = "Journal of Neurology, Neurosurgery & Psychiatry",

issn = "0022-3050",

publisher = "BMJ Publishing Group",

number = "6",

}

TY - JOUR

T1 - Elevated cerebrospinal fluid vasopressin in motor neuron disease

AU - Seckl, J R

AU - Lightman, S L

AU - Guiloff, R J

PY - 1987

Y1 - 1987

N2 - CSF vasopressin levels were significantly elevated in eight patients with motor neuron disease (2.5 +/- 0.4 pmol/l) compared with controls (0.7 +/- 0.1 pmol/l). CSF oxytocin and plasma vasopressin concentrations were similar in the two groups. This finding may be a primary part of the disease process or an epiphenomenon related to increased autonomic and descending pathway activity secondary to abnormal function and/or loss of anterior horn cells.

AB - CSF vasopressin levels were significantly elevated in eight patients with motor neuron disease (2.5 +/- 0.4 pmol/l) compared with controls (0.7 +/- 0.1 pmol/l). CSF oxytocin and plasma vasopressin concentrations were similar in the two groups. This finding may be a primary part of the disease process or an epiphenomenon related to increased autonomic and descending pathway activity secondary to abnormal function and/or loss of anterior horn cells.

U2 - 10.1136/jnnp.50.6.795

DO - 10.1136/jnnp.50.6.795

M3 - Article

C2 - 3612158

SN - 0022-3050

VL - 50

SP - 795

EP - 797

JO - Journal of Neurology, Neurosurgery & Psychiatry

JF - Journal of Neurology, Neurosurgery & Psychiatry

IS - 6

ER -

Elevated cerebrospinal fluid vasopressin in motor neuron disease

Abstract / Description of output

Access to Document

Fingerprint

Cite this