EMAGE: Electronic Mouse Atlas of Gene Expression

Lorna Richardson, Peter Stevenson, Shanmugasundaram Venkataraman, Yiya Yang, Nick Burton, Jianguo Rao, Jeffrey H Christiansen, Richard A Baldock, Duncan R Davidson

Research output: Contribution to journalArticlepeer-review

Abstract

The EMAGE (Electronic Mouse Atlas of Gene Expression) database ( http://www.emouseatlas.org/emage ) allows users to perform on-line queries of mouse developmental gene expression. EMAGE data are represented spatially using a framework of 3D mouse embryo models, thus allowing uniquely spatial queries to be carried out alongside more traditional text-based queries. This spatial representation of the data also allows a comparison of spatial similarity between the expression patterns. The data are mapped to the models by a team of curators using bespoke mapping software, and the associated meta-data are curated for accuracy and completeness. The data contained in EMAGE are gathered from three main sources: from the published literature, through large-scale screens and collaborations, and via direct submissions from researchers. There are a variety of ways to query the EMAGE database via the on-line search interfaces, as well as via direct computational script-based queries. EMAGE is a free, on-line, community resource funded by the Medical Research Council, UK.
Original languageEnglish
Pages (from-to)61-79
Number of pages19
JournalMethods in Molecular Biology
Volume1092
DOIs
Publication statusPublished - 17 Oct 2013

Fingerprint Dive into the research topics of 'EMAGE: Electronic Mouse Atlas of Gene Expression'. Together they form a unique fingerprint.

Cite this