Enantioselective Rhodium-Catalyzed Addition of Potassium Alkenyltrifluoroborates to Cyclic Imines

Yunfei Luo, Andrew J. Carnell, Hon Wai Lam

Research output: Contribution to journalArticlepeer-review

Abstract

Cyclic imines, in which the C[DOUBLE BOND]N bond is constrained in the Z geometry, have been identified as highly effective substrates for enantioselective rhodium-catalyzed additions of potassium alkenyltrifluoroborates. Not only is the alkene in the products a useful functional handle for subsequent manipulations, products containing aryl sulfamates may be employed in nickel-catalyzed Suzuki–Miyaura and Kumada coupling reactions to generate further compounds of interest.
Original languageEnglish
Pages (from-to)6762-6766
Number of pages5
JournalAngewandte Chemie International Edition
Volume51
Issue number27
DOIs
Publication statusPublished - Jul 2012

Keywords

  • alkenyltrifluoroborates
  • asymmetric catalysis
  • enantioselectivity
  • imines
  • rhodium

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