Encoded peptide libraries and the discovery of new cell binding ligands

Nina Svensen, Juan Jose Diaz-Mochon, Mark Bradley

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10 000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified.

Original languageEnglish
Pages (from-to)7638-7640
Number of pages3
JournalChemical Communications
Volume47
Issue number27
DOIs
Publication statusPublished - 2011

Keywords / Materials (for Non-textual outputs)

  • NUCLEIC-ACID
  • MICROARRAYS
  • INTEGRIN
  • IDENTIFICATION
  • PNA
  • ADHESION
  • RECEPTOR
  • IMMOBILIZATION
  • STABILITY
  • SELECTION

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