Endoscopic versus Laparoscopic Management of Non-Invasive Upper Tract Urothelial Carcinoma (UTUC): 20-year Single Centre Experience

Mark L Cutress, Grant D Stewart, Edward C G Tudor, Eric A Egong, Simon Wells-Cole, Simon Phipps, Ben G Thomas, Antony C P Riddick, S Alan McNeill, David A Tolley

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To compare the outcomes of endoscopic surgery (Endo) to laparoscopic nephroureterectomy (LNU) for the management of specifically non-invasive UTUC. MATERIALS & METHODS: A retrospective, database review identified consecutive patients with clinically non-invasive UTUC who underwent Endo (n=59; via ureteroscopic ablation or percutaneous resection) or LNU (n=70) at a single-centre, over 20 years (1991-2011). Overall survival (OS), UTUC-specific survival (DSS), upper-tract recurrence-free survival (UT-RFS), intravesical recurrence-free survival (Bl-RFS), progression-free survival (PFS), and renal unit survival (RUS) were estimated using Kaplan-Meier methods, with differences assessed using the log rank test. RESULTS: The median age and follow-up were 74.8 years and 50 months respectively. Overall renal preservation in the endoscopic group was high (5y RUS 82.5%), although this came at a cost of high local recurrence (Endo 5y RFS 49.3%, LNU 100%, p
Original languageEnglish
Pages (from-to)2054–2061
JournalThe Journal of urology
Volume189
Issue number6
DOIs
Publication statusPublished - 2012

Keywords

  • kidney
  • ureter
  • urinary tract

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