Abstract / Description of output
The development of organ dysfunction is the principal determinant of outcome in acute pancreatitis and is mediated through a systemic inflammatory response characterized by leukocyte and endothelial cell activation. Up-regulation of the endothelial cell adhesion molecules, E-selectin and P-selectin, is important for endothelial/leukocyte interactions. Levels of serum-soluble E-selectin and P-selectin have been suggested as markers of endothelial activation. This study examines the kinetics of serum-soluble selectins in patients with acute pancreatitis complicated by organ dysfunction.
| Original language | English |
|---|---|
| Pages (from-to) | 567-72 |
| Number of pages | 6 |
| Journal | Critical Care Medicine |
| Volume | 29 |
| Issue number | 3 |
| Publication status | Published - 2001 |