Engineered muscle: A tool for studying muscle physiology and function

Alastair Khodabukus, Jennifer Z. Paxton, Kenneth Donnelly, Keith Baar*

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.

Original languageEnglish
Pages (from-to)186-191
Number of pages6
JournalExercise and sport sciences reviews
Volume35
Issue number4
Publication statusPublished - Oct 2007

Keywords

  • tissue engineering
  • exercise
  • fiber type
  • muscle development
  • muscle function
  • SKELETAL-MUSCLE
  • IN-VITRO
  • FIBER-TYPE
  • ELECTRICAL-STIMULATION
  • COLLAGEN GEL
  • RAT MUSCLES
  • MYOSIN
  • EXERCISE
  • ISOFORMS
  • INVITRO

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