Engineering biology for sustainable 1,4-butanediol synthesis

Connor L. Trotter, Gautham S. Babu, Stephen Wallace*

*Corresponding author for this work

Research output: Contribution to journalSpecial issuepeer-review

Abstract / Description of output

Over the past decade, numerous approaches have been taken to replace unsustainable chemical syntheses with green biosynthetic alternatives. In a landmark paper, Yim et al. utilised an in silico-to-in vivo workflow to enable the high-level bioproduction of the unnatural small molecule 1,4-butanediol in the bacterium Escherichia coli.

Original languageEnglish
Pages (from-to)286-288
Number of pages3
JournalTrends in biotechnology
Issue number3
Publication statusPublished - 1 Mar 2023


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