Enhancing strength in mineralized collagen

Fabio Nudelman*, Roland Kröger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Living organisms build an assortment of mineralized tissues by combining biopolymers and minerals. Mineralization is fundamental to many biological functions, ranging from mechanical shock protection by shells, mastication by teeth, linear acceleration detection by otoconia in the inner ear, and body support by skeletons. Scientists have been investigating the material properties of these biominerals with the focus on the combination of organic and inorganic phases and on the organization of microscopic building blocks across several length scales. Bone, which consists of nanocrystalline calcium phosphate in the form of hydroxyapatite embedded within collagen fibrils (1), is one of the most extensively studied biominerals. Fracture resistance of bones is generally attributed to the mineralized collagen fibril (2). On page 188 of this issue, Ping et al. (3) report that mineral growth inside collagen generates a fibril that is under tension, similar to prestressed concrete.

Original languageEnglish
Pages (from-to)137-138
Number of pages2
Issue number6589
Early online date8 Apr 2022
Publication statusE-pub ahead of print - 8 Apr 2022


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