Epigenetic silencing in embryogenesis

Richard R Meehan, Donncha S Dunican, Alexey Ruzov, Sari Pennings

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Transcription profiling of early embryos emphasizes that differential gene expression is a fundamental control mechanism of development. Precise regulatory mechanisms operate on a background of epigenetic changes in chromatin composition, modification, and architecture that are integral for the development of a pluripotent embryo into an adult.
Original languageEnglish
Pages (from-to)241-9
Number of pages9
JournalExperimental Cell Research
Issue number2
Publication statusPublished - 2005


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