Epigenetic silencing in embryogenesis

Richard R Meehan; Donncha S Dunican; Alexey Ruzov; Sari Pennings

doi:10.1016/j.yexcr.2005.06.023

Epigenetic silencing in embryogenesis

Richard R Meehan, Donncha S Dunican, Alexey Ruzov, Sari Pennings

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Transcription profiling of early embryos emphasizes that differential gene expression is a fundamental control mechanism of development. Precise regulatory mechanisms operate on a background of epigenetic changes in chromatin composition, modification, and architecture that are integral for the development of a pluripotent embryo into an adult.

Original language	English
Pages (from-to)	241-9
Number of pages	9
Journal	Experimental Cell Research
Volume	309
Issue number	2
DOIs	https://doi.org/10.1016/j.yexcr.2005.06.023
Publication status	Published - 2005

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10.1016/j.yexcr.2005.06.023

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title = "Epigenetic silencing in embryogenesis",

abstract = "Transcription profiling of early embryos emphasizes that differential gene expression is a fundamental control mechanism of development. Precise regulatory mechanisms operate on a background of epigenetic changes in chromatin composition, modification, and architecture that are integral for the development of a pluripotent embryo into an adult.",

author = "Meehan, {Richard R} and Dunican, {Donncha S} and Alexey Ruzov and Sari Pennings",

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AU - Meehan, Richard R

AU - Dunican, Donncha S

AU - Ruzov, Alexey

AU - Pennings, Sari

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N2 - Transcription profiling of early embryos emphasizes that differential gene expression is a fundamental control mechanism of development. Precise regulatory mechanisms operate on a background of epigenetic changes in chromatin composition, modification, and architecture that are integral for the development of a pluripotent embryo into an adult.

AB - Transcription profiling of early embryos emphasizes that differential gene expression is a fundamental control mechanism of development. Precise regulatory mechanisms operate on a background of epigenetic changes in chromatin composition, modification, and architecture that are integral for the development of a pluripotent embryo into an adult.

U2 - 10.1016/j.yexcr.2005.06.023

DO - 10.1016/j.yexcr.2005.06.023

M3 - Article

C2 - 16112110

SN - 0014-4827

VL - 309

SP - 241

EP - 249

JO - Experimental Cell Research

JF - Experimental Cell Research

IS - 2

ER -

Epigenetic silencing in embryogenesis

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